I could have missed it within the detailed manuscript but did the authors detect any psychosocial stress related hormones such as glucocorticoids, catecholamines, growth hormone or prolactin in the grey/white hair fibres. A new research report revealed by Transparency Market Analysis talks about the general working dynamics of the global veterinary vaccines market and the elements influencing its growth. However, though not a direct marker of senescence, previous work has showed that HF aging is related to a marked decline in 2 hair keratins and 7 keratin-associate proteins (KAPs) (Giesen et al., 2011). Our proteomic experiment on the one-hair from which we analyzed 6 segments equally confirmed a downregulation of 4 of those aging-related keratins/KAPs (KRT33A, KRTAP4-2, KRTAP4-3, KRTAP4-4) within the white segments as in comparison with the previous dark segments. We now briefly mention these findings within the manuscript, but the downregulation for a few of these proteins was not very sturdy, as we previously talked about within the manuscript (p.36) As well as, a current paper in contrast the proteomes of hairs from the identical participant collected at age 1 and forty five (44 years distinction, but early in life) (Plott et al., 2020), discovering 50 proteins upregulated within the older hairs.
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